Description

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TransfectionReagentforU87MGCells(GlioblastomaCells)

• Twocomponentformulationenhanceslipidmediatedtransfectionefficiency
• Optimizedeasy-to-usetransfectionprotocolprovidedfortransfectionofsiRNA,DNA,mRNA,andmicroRNA
• KitincludesTransfectionEnhancerreagentandrecommendedtransfectionprotocol
• Hightransfectionefficacyinthe presenceofserum
• ExpandyourRNAiapplicationwithareagentoptimizedfordeliveryofbothsiRNAandplasmid
• DownloadinvitroU87 transfectionprotocol:[PDF]
• Download U87CRISPR/Cas9transfectionprotocol:[PDF]
• DownloadPowerPointpresentationforU87 cellstransfectionkit:[PPT]
• DevelopedandmanufacturedbyAltogenBiosystems

TransfectionEfficiency:

Reagentexhibitsatleast81%transfectionefficiencyofsiRNAdelivery.TransfectionefficiencywasdeterminedbyqRT-PCR.

TransfectionProtocolandMSDS:

DownloadAltogenBiosystemsU87TransfectionProtocol:[PDF]

DownloadMSDS:[PDF]

U-87MGCellLine:

GlioblastomaisahighlymalignanttumorthatoriginatesfromastrocytesandcanbeextremelydifficulttoerADIcateduetoitcomprisingmanydifferentcelltypes.Someofthesecellsreacttotreatmentwell,andotherscanbeutterlyunresponsivetodrugs,asstatedbytheAmericanBrainTumorAssociation(ABTA).Humancelllinemodelsmayleadtobreakthroughsinbraincancerresearchandinnovativetreatmentapproachesthatareessentialforglioblastomapatients.U-87MGisahumanglioblastomacelllinederivedfromastagethree44-year-oldCaucasianfemale.Ithasepithelialmorphology.GradeIVglioma,alsocalledglioblastomamultiforme(GBM),isthemostcommonprimarymalignantbraintumorwithabout16,000newdiagnoseseachyearintheUnitedStates.GBMshaveaone-yearsurvivalrateofonly29.6%makingitoneofthedeadliesttypesofcancer.U-87isahypodiploidhumancelllinewiththemodalchromosomenumberof44thatoccursin48%ofcells.Therateofhigherploidyisnearly5.9%.TwelveMarkersaresimilarinallcells.ThereisonlyonecopyofnormalX,withN1,N6andN9beingabsent.U-87MGcellsareusedasinvitromodelsofhumanglioblastomacellstoinvestigatethecytotoxiceffectofchemotherapeuticdrugstowardscancercells.TheU-87glioblastomacelllineiswidelyusedintransfectionstudiesand

Altogen Biosystems是一家开发和制造用于生命科学研究，药物发现和开发的转染试剂盒的生物技术公司。转染试剂盒针对特定癌细胞系和原代细胞培养进行了优化，可将生物分子有效递送到靶组织中。通过先进的试剂配方和优化的转染方案实现体外（癌细胞系）和体内（动物组织靶向试剂、癌细胞系）递送货物分子，包括质粒DNA，各种类型的RNA（mRNA，siRNA，shRNA，microRNA），蛋白质和小分子研究。

苏州蚂蚁淘代理Altogen Biosystems在中国的业务。Altogen Biosystems北京代理，Altogen Biosystems华东代理，Altogen Biosystems华北代理，Altogen Biosystems全国代理，Altogen Biosystems华南代理。